HPLC-DAD based chemical profiling of ethanolic and acetone extracts from Moroccan Laurus nobilis L.
1Laboratory of Biology and Health, Biology Department, Faculty of Sciences BP. 2121, Abdelmalek Essaadi University, 93002 Tetouan, Morocco. 2 Laboratory of Natural Resources and Sustainable Development, Faculty of Science, Ibn Tofail University, Morocco. 3 Department of Plant and Environment Protection, National School of Agriculture, Meknes, Morocco. 4 Biology, Ecology and Health Laboratory (UAE/U 08). 5 Faculty of Sciences, BP. 2121, Abdelmalek Essaadi University, Tetouan, Morocco, and the National Federation Associations of Healers and Practitioners of Medicine, the Ministry of Public Health of Chad, N’Djamena, Republic of Chad. 5Laboratory of Plant Biotechnology, Biology Department, Faculty of Sciences BP. 2121, Abdelmalek Essaadi University, 93002 Tetouan, Morocco. Corresp
DOI: https://doi.org/10.37855/jah.2025.v27i04.111
Laurus nobilis L., bay leaf, is widely used as a spice and medicinal herb. The purpose of this research was to characterize the chemical profile of different vegetative organs from Moroccan L. nobilis (leaves, shoots and roots) using HPLC-DAD method. Magnetic stirring extraction was used to extract biomolecules with higher biological activities, utilizing two solvents with higher polarities, namely acetone and ethanol. The extracts were then analyzed by HPLC-DAD technique. The current study revealed that acetone and ethanol are the good solvents for extraction and identification of biomolecules with different percentages (GA (3.78118-5.9418%), Q (15.4982-100%); than ethanol (Q (8.539-25.787%) and R (88.913%)). According to the findings, acetone solvent was shown to be the most efficient solvent for extracting of phenolic compounds from L. nobilis than ethanol. We demonstrated that L. nobilis is a rich source of phenolic compounds, including gallic acid, quercetin, and rutin, that may be used as candidate drugs to cure or prevent diverse and complex disorders, such as Alzheimer's disease, multiple sclerosis, and Parkinson's disease. Although more research in the future should be conducted to reveal the beneficial effects of this plant in different fields, including food, cosmetics, and phytotherapy.
